The present work suggests that protein profiling in saliva may provide a tool for determining differences in risk for erosive tooth wear. This may be of value when determining lifetime risks of loss of dental structure. To identify the risk at an early stage of the disease gives us the opportunity to implement proper individualized prevention

Salivary flow rate exerts an essential impact on the development and progression of dental erosion. In this work, the experimental dental erosion in non-obese diabetic (NOD) mice with reduced salivary flow rate was induced, and the erosive effect of acidic drinks on their dentition was studied.

Dental erosive wear is a multifactorial condition of high prevalence. Nowadays, there is an emphasis on discovering individual genetic predisposition for the development of this condition. Aquaporins (AQPs) are water channel proteins expressed in salivary glands, as well as during tooth development. They are involved in salivary secretion and composition and linked to physiological protection of the oral cavity.
The aim of this study was to explore the relationship between different dental erosive wear phenotypes, AQP genes, and selected environmental factors.