In Vitro Effects of Dental Monomer Exposure – Dependence on the Cell Culture Model -

Methacrylate monomers are major components of resin-based biomaterials. The polymerization of these materials is never complete, and methacrylates leaking from cured materials cause exposure of patients. Only some selected methacrylates have thoroughly been tested for possible interaction with living cells. In the current study, we compared the effects of 2-hydroxyethyl-methacrylate (HEMA; a carefully studied methacrylate) […]

NIOM at NSFT winter meeting -

The Norwegian Society of Pharmacology and Toxicology (NSFT) will hold its annual winter meeting at Beitostølen, Norway, 23-26 January 2020. Among NIOMs representatives you can find this trio: Bergitte Olderbø, Solveig Uvsløkk, og Mathias Fon. Bergitte, Solveig, and colleagues, are there with the poster: “The in vitro toxicity of a dental resin monomer varies among […]

NIOM at NSFT winter meeting, 2019 -

The Norwegian Society of Pharmacology and Toxicology (NSFT) will hold its 47th annual winter meeting at Beitostølen, Norway, 24-27 January 2019

Toxicity of combined exposure of HEMA and nicotine in PE/CA-PJ49 cells -

This abstract was presented at The Norwegian Society of Pharmacology and Toxicology (NSFT) 47th annual winter meeting at Beitostølen, Norway, 24-27 January 2019.

Effects of Nrf2 signaling on cytotoxicity induced by HEMA from dental biomaterials -

INTRODUCTION Resin-based biomaterials used in dentistry consist of methacrylate monomers that are polymerized in situ. The conversion to polymer is never complete and cause patient exposure to electrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA). In addition, dental personnel are exposed through handling of uncured materials. In vitro, methacrylates are reported to be cytotoxic in a […]