Detection of leachables and cytotoxicity after exposure to methacrylate- and epoxy-based root canal sealers in vitro.

, , and | June 19th 2013

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Abstract Root canal sealing materials may have toxic potential in vitro depending on the cell line, cytotoxicity assay, material chemistry, and degree of polymer curing. The aims of the present study were to detect leaching components from epoxy- or methacrylate-based root canal sealers and to investigate the degree of cytotoxicity after exposure to extracts from […]
Bacterial penetration along different root canal filling materials in the presence or absence of smear layer

and | February 11th 2008

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To study the effect of the smear layer on the penetration of bacteria along different root canal filling materials and to examine the dentine/sealer and sealer/core material interfaces for the presence of bacteria.
Cytotoxicity of new resin-, calcium hydroxide- and silicone-based root canal sealers on fibroblasts derived from human gingiva and L929 cell lines

, , and | February 10th 2007

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To assess ex vivo the cytotoxic effects of five new root canal sealers (RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal) and three existing products (AH Plus, RoekoSeal and Apexit) using primary human gingival fibroblasts (HGF) and a mouse fibroblast cell line, L929.