Proteome Changes Indicate Oxidative Stress and Protein Damage after Methacrylate Exposure in Human Monocyte Cell Line

March 13th 2016

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To study the initial changes in the proteome in a human monocyte cell line after exposure to methacrylate monomer
Sub-lethal Concentrations of HEMA alter Protein Expression in Human Monocytes

, , , , and | September 20th 2014

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Several in vitro studies have shown increased intracellular level of reactive oxygen species (ROS) after exposure to 2-hydroxyethyl methacrylate (HEMA), a commonly used monomer in resin-based dental materials. This study aimed to investigate the initial changes of the proteome in a human monocyte cell line after exposure to HEMA by using Stable Isotope Labelling with Amino Acids in Cell culture (SILAC).