Effect of chlorhexidine digluconate on antimicrobial activity, cell viability and physicochemical properties of three endodontic sealers -

The main hypothesis of the study as rejected as exposure to CHX affected sealers’ properties. CHX in contact
with sealer surfaces improved the antibacterial properties of the sealer leachates and reduced cell viability for all sealer leachates, except for freshly mixed PCS. Among the tested sealers, BioRoot RCS leachates presented the highest antibacterial properties and cell viability with and without CHX contact.

Photoactive Zr-aromatic hybrid thin films made by molecular layer deposition -

In this work, we have developed a new MLD process for fabricating photoactive hybrid thin films based on Zr clusters and aromatic 25D-BDC organic linkers. The amorphous and uniform films display high absorption in the visible part of the spectrum. Moreover, we show that the type of the organic ligand and its functional groups can be used to tune the optical properties of Zr-organic hybrids, as shown by the Zr-2A-BDC and Zr-26-NDC systems in this work.

The dentine-sealer interface: Modulation of antimicrobial effects by irrigation -

The aim of this study was to assess whether sodium hypochlorite (NaOCl) or chlorhexidine (CHX) and two irrigation protocols may alter the antibacterial properties of dentine and three endodontic sealers using a novel ex vivo tooth model.

Antimicrobial and physicochemical characterization of endodontic sealers after exposure to chlorhexidine digluconate -

The primary aim of root canal treatment of teeth with apical periodontitis is to eliminate the microbial load from the root canal system and promote periapical healing. Meticulous mechanical debridement of the root canal system significantly reduces the bacterial load and is considered important in canal disinfection. However, complete elimination of all microorganisms is challenging, as viable bacteria potentially remain on the dentin walls and inside dentinal tubules, both in planktonic forms and biofilms. About 35% of the root canal area is left untouched when conventional rotary and hand instruments are used. Therefore, disinfection with irrigation solutions during root-canal treatment and thereafter obturation of the root canal are important factors to reduce the amount and growth of residual bacteria.

Antimicrobial photodynamic treatment of oral infections -

The increased occurrence of antibiotic resistance in general necessitates development of alternative antimicrobial drugs or methods. Further, certain cases of periodontitis respond poorly to conventional treatment. The principle of photodynamic therapy, currently used against certain cancers, may be a practical treatment modality for oral infections, presumably with low possibility for development of resistance. The treatment requires the presence of light-absorbing molecules (photosensitizer; PS) and irradiation with a light source emission that spectrally matches the light-absorption of the PS.