In this work, we have developed a new MLD process for fabricating photoactive hybrid thin films based on Zr clusters and aromatic 25D-BDC organic linkers. The amorphous and uniform films display high absorption in the visible part of the spectrum. Moreover, we show that the type of the organic ligand and its functional groups can be used to tune the optical properties of Zr-organic hybrids, as shown by the Zr-2A-BDC and Zr-26-NDC systems in this work.

Abstract Natural deep eutectic solvents (NADES) are a third class of liquids, separate from water and lipids. Some NADES, especially those containing organic acids, have been suggested to possess antimicrobial properties. Such properties may be advantageous when NADES are used as solvents in e.g. antimicrobial photodynamic therapy. However, to control the toxicity of acid-containing NADES, […]

Lumichrome (Lc) is a photodegradation product of riboflavin. It is more photostable and a more efficient photogenerator of singlet oxygen than riboflavin. Lc absorbs mainly in the UVA range. Cyclodextrins (CDs) are reported to be very efficient solubility enhancers of Lc in aqueous solutions. A 1:1 inclusion complex has been predicted between Lc and α and βCDs (Terekhova, Kumeev et al. 2011). The aim of the present study was to evaluate the influence of CDs on solubility and on the bacterial phototoxicity of Lc in vitro.

Neutral porphyrins for antibacterial photodynamic therapy (aPDT) have received little attention due to their tendency to aggregate in aqueous media and reports of low phototoxic effect. These compounds may be less toxic to cells than positively and negatively charged photosensitisers.

Curcumin is currently under investigation as a potential photosensitiser in antimicrobial photodynamic therapy (aPDT). Previous studies have demonstrated high phototoxicity towards Gram-positive (G+) bacteria, but lower effect on Gram-negative (G-) bacteria.