Application of nanovehicles in preparations for antimicrobial photodynamic therapy (aPDT)
Hanne Hjorth Tønnesen, Anne Bee Hegge and Ellen Bruzell | April 13th 2013
Topical application is the preferred administration route of the photosensitizer (PS) in antimicrobial photodynamic therapy (aPDT), e.g. for the treatment of infections in the oral cavity or skin. The drug formulation should allow for a sufficient contact time between the preparation and tissue, a rapid release of PS, and a selective uptake of PS in bacteria.