Victoria J. Valerón Bergh defended her PhD degree in pharmaceutics -

The dissertation title was “Pharmaceutical preformulation and formulation of an alloxazine and a porphyrin-type photosensitizer”.

Evaluation of material suitability for nanoparticle-based coatings and further antimicrobial treatment -

Dental materials are easily colonized by bacteria, and microbial attack is the main cause of dental implant failure and periodontitis. The aim of this project was to formulate nanoparticle-based (NPsol) coatings that reduce bacterial adherence on materials used in dentistry. Pre-treatment of the surfaces with such coatings could create a time window that allows for killing of the surrounding bacteria prior to or shortly after adhesion. One option is to apply antimicrobial photodynamic therapy (aPDT).

Photoinactivation of bacteria by lumichrome: Influence of formulation and preparation method. -

Lumichrome, a photodegradation product of riboflavin, is an endogenous compound in humans. The compound is more photostable and a more efficient photogenerator of singlet oxygen than riboflavin. It absorbs radiation in the UVA and blue light region, which can be an advantage in aPDT of superficial infections.

Formulation and characterization of lyophilized curcumin solid dispersions for antimicrobial photodynamic therapy (aPDT): Studies on curcumin and curcuminoids LII -

Bacterial resistance to antibiotics is increasing and alternative antibacterial treatments like antimicrobial photodynamic therapy (aPDT) are needed. Curcumin is under investigation as a potential photosensitizer in aPDT.

Supersaturation and supersaturated drug delivery systems to surpass the outher membrane barriers of Gram negative bacteria in antimicrobial photodynamic therapy (aPDT). -

Bacterial resistance towards antibiotics is increasing. Especially Gram negative (G-) pathogenic bacteria are responsible for serious nosocomial infections. Novel treatment strategies such as antimicrobial photodynamic therapy (aPDT) are needed to fight such infections.