Antibacterial photodynamic therapy for treatment of oral biofilms related to periodontal and peri-implant diseases -

Abstract from Håkon Valens lecture at symposium MED-10 Dentistry. (Organized by Ellen Bruzell). ESP-IUPB World Congress, Light & Life, Barcelona, Spain. August 25-30. 2019. Oral biofilm formation around teeth and dental implants may cause inflammation of the surrounding tissue, which may lead to breakdown of the attachment of the tooth or implant. Ultimately, if left […]

Kontrol og bekæmpelse af dental biofilm -

Control and eradication of dental biofilm. This article gives a brief overview of antimicrobial compounds used for biofilm control and new technologies and strategies to combat dental biofilms.

Victoria J. Valerón Bergh defended her PhD degree in pharmaceutics -

The dissertation title was “Pharmaceutical preformulation and formulation of an alloxazine and a porphyrin-type photosensitizer”.

Solid dispersions for preparation of phototoxic supersaturated solutions for antimicrobial photodynamic therapy (aPDT): Studies on curcumin and curcuminoides L -

Curcumin is under investigation as a potential photosensitizer (PS) in antimicrobial photodynamic therapy (aPDT). The therapeutic potential of curcumin as a PS is limited by its low aqueous solubility, susceptibility to hydrolytic and photolytic degradation, and limited phototoxicity toward Gram negative (G−) bacteria.

Photoinactivation of Stahpylococcus epidermidis biofilms and suspensions by the hydrophobic photosensitizer curcumin- effect of selected nanocarrier Studies of curcumin and curcuminoides XLVII -

Solubilization and stabilization from rapid degradation by the use of nanocarriers are necessary to exploit curcumin’s phototoxic potential towards pathogenic bacteria.