Supersaturation and supersaturated drug delivery systems to surpass the outher membrane barriers of Gram negative bacteria in antimicrobial photodynamic therapy (aPDT).
Anne Bee Hegge, Milica Vukicevic, Kristine Opsvik Wikene, Ellen Bruzell and Hanne Hjorth Tønnesen | April 13th 2013
Bacterial resistance towards antibiotics is increasing. Especially Gram negative (G-) pathogenic bacteria are responsible for serious nosocomial infections. Novel treatment strategies such as antimicrobial photodynamic therapy (aPDT) are needed to fight such infections.