In this study we aimed to further map the suggested relation between GSH-depletion and methacrylate toxicity by comparing the molecular effects of methacrylate exposure and GSH-depletion by inhibiting GSH-synthesis.

The toxicity of methacrylate resin-based root canal sealers with sealers based on epoxy resin and silicone by two-well established cell culture methods.

Natural curcumin was evaluated as a potential photosensitizer for oral applications. The photocytotoxicity of curcumin on salivary gland acinar cells (SM 10-12) was investigated in five aqueous preparations consisting of 5% DMSO, non-ionic micelles, cyclodextrin, liposomes, or a hydrophilic polymer.