Involvement of NADPH Oxidase and iNOS in Rodent Pulmonary Cytokine Responses to Urban Air and Mineral Particles -

We have investigated the potential of two complex mineral particles (feldspar and mylonite), quartz (Min-U-Sil), and suspended particulate matter (SRM-1648) (SPM) from urban air to induce inflammatory cytokine responses in primary rat alveolar type 2 cells and alveolar macrophages, and the involvement of cellular formation of free radicals in these responses.