In Vitro Effects of Dental Monomer Exposure – Dependence on the Cell Culture Model -

Methacrylate monomers are major components of resin-based biomaterials. The polymerization of these materials is never complete, and methacrylates leaking from cured materials cause exposure of patients. Only some selected methacrylates have thoroughly been tested for possible interaction with living cells. In the current study, we compared the effects of 2-hydroxyethyl-methacrylate (HEMA; a carefully studied methacrylate) […]

Clinical relevance of HEMA-toxicity studies -

Several studies show “leakage” of methacrylates during, and shortly after, treatment resin based dental materials. Read about the clinical relevance here.

The dental monomer HEMA causes proteome changes in human THP‐1 monocytes -

Resin-based biomaterials are widely used in medical and dental treatment, and both clinicians and patients are exposed to the materials.
The present approach to analyzing the toxic potential of HEMA yielded information on interactions with living cells is not previously reported. This detailed information is of great value to make better predictions of possible side effects in the clinic.

Toxicity of plast materials -

The term «resin-based dental materials» refers to dental materials containing polymers. Usually, these polymers are formed by in situ polymerization of methacrylate monomers.

Identification of methacrylates and acrylates in dental materials by mass spectrometry -

The electron-impact and methane chemical-ionization mass spectra of selected methacrylate and acrylate monomers commonly used in dental materials are reported and discussed.