Summary of: Side effects of external tooth bleaching: a multi-centre practice-based prospective study. -

The study was performed to assess the risk of at-home and in-office bleaching procedures, and to recognise potential predictors for side effects.
Bleaching treatment, irrespective of method, caused a high prevalence of side effects

Hyperspectral imaging/reflectance spectroscopy of mouse oral tissue exposed to high intensity blue light. -

Oral tissues are exposed to optical radiation during various dental treatments and diagnostic methods. However, adverse effects are seldom addressed. Hyperspectral imaging (HSI) and visible near-infrared reflection spectroscopy (VNIRS) were used to observe oral tissue changes in mice exposed to blue light with respect to erythema (erythema index; EI) and pigmentation (melanin index; MI). Pigmented mice (C57BL/6N; ngroup = 3) were exposed on the tongue and the abdominal skin for control or left unexposed. Irradiation was performed with an LED intended for photopolymerisation of dental materials (λpeaks: 409/460 nm) with irradiance ≈ 2 W/cm2 and radiant exposure ≈ 120 J/cm2.

Osteoporosis and periodontal disease -

Primary osteoporosis signifies the loss of trabecular bone mass following menopause and is linked to decreased production of estrogen. The condition increases the risk of traumatic fractures of peripheral bones such as wrist or femur and compression fractures of the spine. The degree of osteoporosis is determined by assessing the mineral density of different skeletal bones. Jawbone, including the tooth supporting alveolar process, may also be affected by osteoporosis.

The development of T cell-dominated inflammatory responses induced by sodium lauryl sulphate in mouse oral mucosa -

The effect of a single time exposure of SLS to the buccal mucosa of mice was compared to one application of the hapten OXA (oxazolone), evaluated by routine histology, immunohistochemistry and ELISA quantifications of cytokines. The SLS concentrations (2%, 4% and 8%) resulted in epithelial surface necrosis at 1-6 h, after 2-6 h accumulation of intra-epithelial neutrophils and at 24 h the main inflammatory cells were mononuclear.

Biotransformation enzymes and lung cell response to 2-hydroxyethyl-methacrylate. -

The aim of this in vitro study was to investigate possible involvement of cytochrome P450 (CYP) enzymes in modifying the toxic potential of 2-hydroxyethyl-methacrylate (HEMA). Primary cultures of CYP expressing rat alveolar type 2 cells were exposed to varying concentrations of HEMA. Nuclear translocation of aryl hydrocarbon receptor (AhR) after HEMA exposure (100 μM) was demonstrated by immunocytochemical staining.