The present study was part of the research project Inhalation and prenatal exposure to phthalates: influence on airway immunology, conducted at the Norwegian Institute of Public Health, and was funded by the Norwegian research council (Research grant number: 228129).

INTRODUCTION Resin-based biomaterials used in dentistry consist of methacrylate monomers that are polymerized in situ. The conversion to polymer is never complete and cause patient exposure to electrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA). In addition, dental personnel are exposed through handling of uncured materials. In vitro, methacrylates are reported to be cytotoxic in a […]

Abstract Objectives 2-Hydroxyethyl methacrylate (HEMA) is a major component of many resin-based dental materials. During and after treatment with these materials, both dental personnel and patients are exposed to HEMA. In vitro studies have demonstrated a cytotoxic potential of HEMA, and reactivity towards cysteine (a nucleophilic amino acid (AA)) in glutathione (GSH) is assumed to contribute to […]

BPA has been reported to leach from some resin-based dental restorative materials and materials used for orthodontic treatment. To confirm and update previous findings, especially in light of the new temporary lower threshold value for tolerable daily BPA intake, leaching of BPA from 4 composite filling materials, 3 sealants and 2 orthodontic bonding materials were investigated.