Wavelength dependent increase in cell sensitivity after glutathione inhibition by methacrylate monomers.
Terje Christensen, Trygve Danielsen, Alicja Jaworska, Gunnar Brunborg and Ellen Bruzell | May 27th 2016
Reduction in the amount of glutathione (GSH) in cells can lead to increased sensitivity to physical and chemical agents. Methacrylate monomers (MM) are precursors of polymethacrylates which are used in dental and medical biomaterials and in a wide variety of other products. MM can increase cell sensitivity to long wavelength ultraviolet and visible radiation. The aim of this study is to elucidate if MM can induce sensitivity also to shorter wavelength radiation.