HEMA reduced GSH levels and decreased IL-1β release from LPS-stimulated macrophages. The role of GSH in the regulation of IL-1β release was explored. GSH depletion alone could not explain the attenuation of LPS-induced IL-1β release. Electrophile reactivity toward other cellular molecules is a new working hypothesis
Polymer-based composites are often the material of choice in restorative dentistry. Composites consist of two main phases; the filler, usually silica particles of various sizes, and the matrix that in general is a mixture of methacrylate monomers.