The effects of dentin pre-treatment with ethylene diamine tetraacetic acid (EDTA) or iodine-potassium iodide (IKI) on the adhesion of a conventional root filling material (gutta-percha and epoxy resin based sealer) and an acrylic-resin-based system with adhesive technology were studied.

Removal of the smear layer may impair sealer adhesion to dentine. Different sealer types require different dentine pretreatments for optimal adhesion