Phototoxicity of curcumin loaded alginate foams to Enterococcus faecalis and Escherichia coil in vitro -

Curcumin loaded alginate foams are proposed for application in antimicrobial photodynamic therapy of infected wounds. The drug loaded foams were formulated to provide a burst release of the photosensitizer when hydrated.

Photokilling of bacteria by curcumin in different aqueous preparations. Studies on curcumin and curcuminoids XXXVII. -

Curcumin has potential as a photosensitiser (PS) in photodynamic therapy (PDT) for localised superficial infections. However, it is a challenge to make an optimal curcumin formulation in which curcumin has acceptable solubility and stability at physiological pH and combined with high selective phototoxic activity towards bacteria.

Studies on curcumin and curcuminoids. XXIX. Photoinduced cytotoxicity of curcumin in selected aqueous preparations. -

Natural curcumin was evaluated as a potential photosensitizer for oral applications. The photocytotoxicity of curcumin on salivary gland acinar cells (SM 10-12) was investigated in five aqueous preparations consisting of 5% DMSO, non-ionic micelles, cyclodextrin, liposomes, or a hydrophilic polymer.