Responses of the pulp–dentin organ to dental restorative biomaterials. -

Placement of a restorative material in dentin produces the possibility of pulpal injury. In vitro studies have shown that the constituents of dental biomaterials have toxic potentials. In the clinical setting, there may be an immediate reaction of the pulp to, for example, acid etching and to the placement of a bonding agent; however, in most cases the remaining dentin serves as protection against long-term or permanent damage to the pulp.