Apoptosis induced by the monomers HEMA and TEGDMA involves formation of ROS and differential activation of the MAP-kinases p38, JNK and ERK.
Jan Tore Samuelsen, Jon Einar Dahl, Stig Karlsson, Else Morisbak and Rune Becher | January 23rd 2007
-
Cytotoxic methacrylate monomers have been identified in aqueous extracts of freshly cured compomers. Some of these compounds, including HEMA and TEGDMA, induce apoptosis and necrosis in vitro.
