Antimicrobial photodynamic therapy for treatment of oral biofilm associated diseases – where we are -

Abstract from Håkon Valens lecture at symposium PDT-4. Human antimicrobial PDT. ESP-IUPB World Congress, Light & Life, Barcelona, Spain. August 25-30. 2019. Bacteria in the oral cavity lives primarily in polymicrobial biofilms. Oral mature biofilms may contain several hundred different bacterial species, and over 600 different species have been shown to colonize the oral cavity. […]

Disputation: Kristine Opsvik Wikene -

MSc. Pharm Kristine Opsvik Wikene will be defending the thesis for the degree of Ph.D. on Monday 26 June, 2017 at the School of Pharmacy, University of Oslo.

Investigation of the antimicrobial effect of natural deep eutectic solvents (NADES) as solvents in antimicrobial photodynamic therapy -

Abstract Natural deep eutectic solvents (NADES) are a third class of liquids, separate from water and lipids. Some NADES, especially those containing organic acids, have been suggested to possess antimicrobial properties. Such properties may be advantageous when NADES are used as solvents in e.g. antimicrobial photodynamic therapy. However, to control the toxicity of acid-containing NADES, […]

Characterization and antimicrobial phototoxicity of curcumin dissolved in natural deep eutectic solvents -

The purpose of the current study was to evaluate the potential of NADES as a solvent for the hydrophobic photosensitizer curcumin for use in antimicrobial photodynamic therapy (aPDT).

Evaluation of material suitability for nanoparticle-based coatings and further antimicrobial treatment -

Dental materials are easily colonized by bacteria, and microbial attack is the main cause of dental implant failure and periodontitis. The aim of this project was to formulate nanoparticle-based (NPsol) coatings that reduce bacterial adherence on materials used in dentistry. Pre-treatment of the surfaces with such coatings could create a time window that allows for killing of the surrounding bacteria prior to or shortly after adhesion. One option is to apply antimicrobial photodynamic therapy (aPDT).