Antibacterial photodynamic therapy for treatment of oral biofilms related to periodontal and peri-implant diseases -

Abstract from Håkon Valens lecture at symposium MED-10 Dentistry. (Organized by Ellen Bruzell). ESP-IUPB World Congress, Light & Life, Barcelona, Spain. August 25-30. 2019. Oral biofilm formation around teeth and dental implants may cause inflammation of the surrounding tissue, which may lead to breakdown of the attachment of the tooth or implant. Ultimately, if left […]

Antibacterial and anti-adhesive properties of Pluronic® F127 solutions in the absence or presence of photoactivation -

INTRODUCTION Staphylococcus epidermidis, a human skin commensal, is the most frequent isolate from infections of medical indwelling devices. This fact reflects the ubiquitous nature of S. epidermidis on the skin and the risk of contamination of a medical device before or during insertion1. A counteraction strategy is to develop coatings of medical devices to reduce […]

Improved antibacterial phototoxicity of a neutral porphyrin in natural deep eutectic solvents -

Neutral porphyrins for antibacterial photodynamic therapy (aPDT) have received little attention due to their tendency to aggregate in aqueous media and reports of low phototoxic effect. These compounds may be less toxic to cells than positively and negatively charged photosensitisers.