This Newsletter consists of a summary from a recently published research paper from NIOM. The effect on macrophages of exposure to filler particles and monomers was investigated. It was found that the release of substances related to tissue defense was reduced after exposure. An attenuated cytokine release may have implications for the macrophage immune response and result in impaired bacterial clearance from for example a periodontal pocket. Read the article: Dental composites modulate cytokine signaling in cells.


In addition, we present a method that can be used for identification of microorganisms and for testing the effect of antimicrobial substances and techniques: Microbiology testing and research.