The lifespan of a resin-based restoration is limited, with the main reason for failure being secondary caries. Bioﬁlm formation at the tooth–material interface is a necessary etiological agent for caries development. Dental materials with antimicrobial properties may reduce formation of bioﬁlm and thus increase the longevity of restorations. This study aimed to investigate the eﬀect of methacrylated chitosan (CH-MA), incorporated into the polymeric network of an experimental dental composite and adhesive, on bioﬁlm growth of Streptococcus mutans and to assess the mechanical properties of the modiﬁed materials. The methacrylation of low-molecular-weight chitosan was achieved and bioﬁlm studies conﬁrmed the antibacterial eﬀect of the modiﬁed polymer in solution. Methacrylated chitosan was incorporated into an experimental composite and adhesive, and the modiﬁed materials reduced the formation of S. mutans bioﬁlm. The incorporation of CH-MA did not alter the bond strength of the adhesives. However, the amount of CH-MA in composite that is required to elicit an antibacterial response challenges the mechanical properties of the material. The hardness and ﬂexural strength of the composite decreased with increasing amounts of CH-MA. However, ﬂexural strength values still met the requirement in the ISO standard.
Eﬀect of methacrylated chitosan incorporated in experimental composite and adhesive on mechanical properties and bioﬁlm formation.
Stenhagen ISR, Rukke HV, Dragland IS, Kopperud HM.
Eur J Oral Sci 2019; 127: 81–88.