The aim of this longitudinal study was to compare caries incidence in sound approximal surfaces adjacent to newly placed composite restorations with the caries incidence in corresponding surfaces in contralateral teeth without any restorations in contact; and to assess risk factors for dentine caries development on adjacent and control surfaces.

The European Commission asked its independent Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) to provide a risk assessment on dental amalgam and alternatives such as resin-based composites, glass ionomer cements, ceramics and gold alloys to update the SCENIHR’s 2008 Opinion in light of new developments and data.

The effect of anatomic contour design in all or parts of zirconia crowns is uncertain regarding clinical reliability and survival rates.

The term «resin-based dental materials» refers to dental materials containing polymers. Usually, these polymers are formed by in situ polymerization of methacrylate monomers.

The in vitro adsorption and retention of liposomes onto four common types of dental restorative materials (conventional and silorane-based resin composites as well as conventional and resin-modified glass ionomer cements (GIC)) have been investigated due to their potential use in the oral cavity.

The purpose of the current study was to evaluate the potential of NADES as a solvent for the hydrophobic photosensitizer curcumin for use in antimicrobial photodynamic therapy (aPDT).

To assess risk factors for caries development on approximal surfaces in contact with newly placed Class II composite restorations.

Lumichrome (Lc) is a photodegradation product of riboflavin. It is more photostable and a more efficient photogenerator of singlet oxygen than riboflavin. Lc absorbs mainly in the UVA range. Cyclodextrins (CDs) are reported to be very efficient solubility enhancers of Lc in aqueous solutions. A 1:1 inclusion complex has been predicted between Lc and α and βCDs (Terekhova, Kumeev et al. 2011). The aim of the present study was to evaluate the influence of CDs on solubility and on the bacterial phototoxicity of Lc in vitro.

Dental materials are easily colonized by bacteria, and microbial attack is the main cause of dental implant failure and periodontitis. The aim of this project was to formulate nanoparticle-based (NPsol) coatings that reduce bacterial adherence on materials used in dentistry. Pre-treatment of the surfaces with such coatings could create a time window that allows for killing of the surrounding bacteria prior to or shortly after adhesion. One option is to apply antimicrobial photodynamic therapy (aPDT).

The aim of this study was to investigate the effect of silane in the repair of old and new resin-composite restorations.

Abstract Objective The aims of this study were to investigate the release of element from, and the biological response in vitro to, cobalt–chromium alloys and other base–metal alloys used for the fabrication of metal-ceramic restorations. Material and methods: Eighteen different alloys were investigated. Nine cobalt–chromium alloys, three nickel–chromium alloys, two cobalt–chromium–iron alloys, one palladium–silver alloy, […]

In the light of new developments and studies on dental amalgam a request was submitted by the Commission to update the SCENIHR opinion produced in 2008 on the safety and performance of both dental amalgam and possible alternatives, such as resin-based composites, glass ionomer cements, ceramics and gold alloys.

Blue light and ultraviolet radiation can cause acute eye hazards. Further, increasing evidence suggests that blue light contributes to chronic diseases, such as cataracts and age-related macular degeneration. The use of optical radiation protective devices, such as goggles, is a simple means to avoid eye damage when working with high irradiance sources.

The aim of this study was to investigate the in vitro aPDT effect of various lumichrome pharmaceutical formulations

The aim of this study was to use a clinically relevant test method to evaluate the effect of the curvature of the cervical crown margins on load at fracture

In this study, the viability of human lung epithelial cells, BEAS-2B, was investigated after exposure to this monomer. Exposure to HEMA reduced the viability of the BEAS-2B cells as a result of increased apoptosis, interruption of the cell cycle, and decreased cell proliferation.

Organisms living in aquatic ecosystems may experience high doses of natural UV radiation. UV radiation penetrates the water column down to several meters. The penetration depth differs depending on the contents of particles, dissolved matter or pollutants. The aim of this study was to establish the dose-response relationship of phenotypic changes caused by UV.

Gold inlays have for a long time been known as high quality restorations. Since dental amalgam is no longer applicable as filling material in Norway, the need for gold inlays has expanded, especially in patients having high chewing force and tooth abrasions who need replacement of their old amalgam fillings.

Neutral porphyrins for antibacterial photodynamic therapy (aPDT) have received little attention due to their tendency to aggregate in aqueous media and reports of low phototoxic effect. These compounds may be less toxic to cells than positively and negatively charged photosensitisers.

To compare two home-based over-the-counter (OTC) bleaching tray products with similar hydrogen peroxide (HP) concentrations with respect to tooth lightening efficacy and potential to induce negative side effects in tobacco- and non-tobacco users as well as degree of satisfaction with product handling. The HP concentrations were near the regulation limit for bleaching products of 6% set by the European Union in 2011.

Bisphenol A (BPA) is a key building block of polycarbonate plastic and a precursor for the manufacturing of monomers of epoxy resins. The BPA exposure of the general population is via food as a result of the use of BPA in food packaging and via skin as a result of contact with thermal paper. The vast majority of the population (91–99%) has detectable levels of BPA-conjugates in their urine. BPA is also present in medical devices including implants, catheters, tubing, and some dental materials.

Placebo was originally defined as an inactive medication giving a positive effect, whereas nocebo gives the opposite result. Both situations are based on expectations, of positive or negative kind.

With equipment for computer-aided design and manufacturing (CAD/CAM) in the dental office, the dentist again becomes his own dental technician. While the equipment itself is not subject to health-related regulation, the European Medical Devices Directive imposes requirements on the prosthodontic devices it produces

A study was performed to assess 13 different eye protection filters, glasses and shields, intended for use with dental material light curing procedures as a follow- up to a similar investigation in 200

Chitosan is produced commercially from crab and shrimp shell wastes with different degrees of deacetylation and molecular masses. Because of chitosan’s promising biological activities, including non-toxicity and antimicrobial activity, it is used for a variety of purposes in food production, medicine, agriculture, cosmetics, and biotechnology.

This Guidance addresses the use of nanomaterials in medical devices and provides information for risk assessors regarding specific aspects that need to be considered in the safety evaluation of nanomaterials. According to the EU Recommendation for the definition of a nanomaterial (Commission Recommendation 2011/696/EU, EC 2011) any particulate substance with at least one dimension in the size range between 1 and 100 nm is considered a nanomaterial.

A study was performed to assess 13 different eye protection filters, glasses and shields, intended for use with dental material light curing procedures as a follow-up to a similar investigation in 2006. To assess the safety and efficiency, spectra of curing lamps and filters were measured using a spectroradiometric instrument and integrating sphere.

The buildup of dental plaque is the first step towards the oral diseases caries and periodontitis. Identification of pathogenic substances and matrix components is of importance when choosing an appropriate treatment plan. Hyperspectral imaging combines spectral- and spatial information, providing new possibilities for precise optical characterization of biological tissue [1,2], including dental plaque.

Det settes søkelyset på forhold man kan stå overfor ved valg av tannerstatninger, om det er forskjell på et arbeid som er laget i Norge kontra et arbeid som er produsert i utlandet. To ganger tidligere (2008, 2010) er forholdet mellom oppgitt og analysert sammensetning av legeringselementene på importarbeid blitt undersøkt ved NIOM.

Despite the high fracture strength of modern dental core ceramics, fracture is a common cause of failure in clinical trials. Fracture origins are typically in the crown margin in the appoximal region where the margin curves upwards. The scientific evidence for optimal marginal design of preparation is limited. The aim was to use a clinically relevant test method to evaluate the effect on strength of the cervical margin’s curvature of ceramic crowns.

To evaluate the effect of surface treatments and bonding systems on the repair bond strength between composite materials after one and 12 months of storage, using an improved microtensile test method.

Several in vitro studies have shown increased intracellular level of reactive oxygen species (ROS) after exposure to 2-hydroxyethyl methacrylate (HEMA), a commonly used monomer in resin-based dental materials. This study aimed to investigate the initial changes of the proteome in a human monocyte cell line after exposure to HEMA by using Stable Isotope Labelling with Amino Acids in Cell culture (SILAC).

Pelagic embryos of fish may be exposed to high doses of natural UV radiation. Shortwave UV, UVB, as well as UVA may penetrate the water column to depths of several meters. The penetration depth differs depending on the contents of particles, dissolved matter or pollutants. Pollutants may also interact photochemically with UV- and visible radiation.

I mai 2014 deltok NIOM på et symposium ved Dalhousie University, Halifax, Canada om lysherding i odontologi. Det var 40 deltakerne fra ulike akademiske miljø og industrien, som utarbeidet retningslinjer for klinisk relevant valg og bruk av herdelamper (1)

Bacterial plaque adheres to resin based restorative materials to a larger extent than many other biomaterials, increasing the risk of secondary caries. Therefore, research has focused on adding antibacterial activity to such materials. One method has been to add soluble disinfectants such as chlorhexidine, benzalconium chloride, triclosan, octenidin, or antioxidants such as epigallocathechin to the […]

The degree of conversion (DC) of mixtures with higher content of bis-EMA is affected by the presence of bis-GMA at lower energy density delivered from the curing device, suggesting that the restrictions caused by the presence of hydrogen bonds is dependent of the irradiation time used

The aim of this study was to evaluate the in vitro phototoxic potential of synthetic asymmetric and glycosylated curcuminoids on planktonic model bacteria by counting the colony forming units.

Comparison of fracture strength and fracture modes of different all-ceramic crown systems is not straightforward. Established methods for reliable testing of all-ceramic crowns are not currently available. Published in-vitro tests rarely simulate clinical failure modes and are therefore unsuited to distinguish between the materials. The in-vivo trials usually lack assessment of failure modes. Fractographic analyses show that clinical crowns usually fail from cracks initiating in the cervical margins, whereas in-vitro specimens fail from contact damage at the occlusal loading point. The aim of this study was to compare three all-ceramic systems using a clinically relevant test method that is able to simulate clinical failure modes.

Curcumin is currently under investigation as a potential photosensitiser in antimicrobial photodynamic therapy (aPDT). Previous studies have demonstrated high phototoxicity towards Gram-positive (G+) bacteria, but lower effect on Gram-negative (G-) bacteria.