Members of the dental team are exposed daily to biological, chemical and physical agents. These vary for example, from microorganisms to noise, and are present in forms as diverse as aerosols and gasses. National and international directives, legislation and guidelines for infection control, and occupational health issues intended for the dental clinic, govern the physical and other types of protection required. In addition, it is important to be acquainted with the justification for any specific protective item, when and when not to use it and when an upgrade is required. (Article in Danish)

Bacterial biofilm elimination using gold nanorod localised surface plasmon resonance generated heat.
Highlights:
A technique for antibiotic replacement using heat for biofilm elimination is proposed.
Gold nanorods exhibit localised surface plasmon resonance upon optical irradiation and when relaxing, absorbed energy is dissipated as heat, which is utilized to kill bacteria.
After 5 minutes of near infrared irradiation an average of 71% of early biofilms were eliminated.

Abstract Natural deep eutectic solvents (NADES) are a third class of liquids, separate from water and lipids. Some NADES, especially those containing organic acids, have been suggested to possess antimicrobial properties. Such properties may be advantageous when NADES are used as solvents in e.g. antimicrobial photodynamic therapy. However, to control the toxicity of acid-containing NADES, […]

Bonding of zirconia crowns and bridges to abutments is important, not only bonding of the thin resin layer to the abutment, but also bonding to the zirconia ceramic is crucial. Both mechanical and chemical adhesion are desired. Mechanical retention of dental porcelain achieved by etching with moderately concentrated hydrofluoric acid is not possible with zirconia ceramics. The purpose of this study was to show that etching is possible with relative low melting fluoride compounds such as ammonium hydrogen difluoride and potassium hydrogen difluoride.

In this study we aimed to further map the suggested relation between GSH-depletion and methacrylate toxicity by comparing the molecular effects of methacrylate exposure and GSH-depletion by inhibiting GSH-synthesis.

We are daily exposed to a variety of chemicals. One example is the chemical Bisphenol A (BPA). Animal studies indicate that BPA has effects on liver, kidney and breast tissue. Possible endocrine disruption effects contribute to uncertainty around BPA.

HEMA reduced GSH levels and decreased IL-1β release from LPS-stimulated macrophages. The role of GSH in the regulation of IL-1β release was explored. GSH depletion alone could not explain the attenuation of LPS-induced IL-1β release. Electrophile reactivity toward other cellular molecules is a new working hypothesis

The study aimed to investigate dentists’ exposure to curing light and to obtain information about the dentists’ knowledge on practical use and technical features of their curing lights as well as their safety awareness.

One of the most significant medical achievements in human medicine during the 20th century was the discovery and introduction of antibiotics. However, a short time after the introduction of new antibiotic compounds, resistant bacteria were discovered.

NIOM’s purpose is to ensure that the dental materials and products, used in dental care in the Nordic countries, meet the health and technical requirements which are in place regarding development in the area.

Restorative dental treatment still lays claim to a large proportion of dentists’ working day. After the phase-out of amalgam as a restorative material, composite resin has become the dominating material of choice among dentists.

Abstract In this article we are looking at the development of composite restorative materials. We discuss the composition of the resin matrix, and describe the introduction of some new monomers. We also comment on the development of fillers. Some materials are discussed in more detail. Bulk-fill materials do not seem to be essentially different to […]

The root canal filling concludes the classical triad in endodontic treatment: biomechanical instrumentation, disinfection and obturation. The purpose of the root canal filling is to prevent penetration of bacteria into the root canal and to prevent access of nutrients and growth of residual bacteria.

Different dental ceramics available today including a classification, mechanical properties and a description of processing techniques with emphasis on the zirconia materials.

Cobalt-chromium alloys are now commonly used for fixed dentures and single crowns. The alloys are attractive because they are light and provide high stiffness due to their high elastic modulus (Young’s modulus) compared with noble metal alloys, pure titanium or titanium alloys.

Abstract The use of dental and surgical loupes is increasing in odontology and medicine. During dental treatments this use is often combined with bright blue light sources such as from dental material curing lights and/or lights attached to the loupes. By the aid of an experimental model we investigated whether the time to reach the […]

Tandrestaureringsmaterialer indeholder en mængde forskellige stoffer med ulige biologiske egenskaber. I mundhulen udsættes materialerne for både mekaniske, kemiske, mikrobielle og enzymatiske påvirkninger, og substanser kan frigives fra materialerne

Whether single crowns produced by computer-aided design and computer-aided manufacturing (CAD-CAM) have an internal fit comparable to crowns made by lost-wax metal casting technique is unknown.

The degree of conversion (DC) and monomer leaching of three experimental urethane dimethacrylate (UEDMA)-hydroxypropyl methacrylate (HPMA)-based resin systems were studied.

Mange forskere hevder at regelmessig tilførsel av probiotika også kan ha en hemmende effekt på kariesutvikling og periodontal patologi ved at tilførte bakterier konkurrerer med patogener både med hensyn til adhesjon, næringsstoffer og vekstfaktorer

The aim of this study was to investigate the antibacterial and antibiofilm properties of low viscosity chitosan on S. epidermidis growth and biofilm formation.

This study aimed to investigate dentists’ treatment choices concerning “repair or replacement” of defective restorations.

The study aimed to explore the variability between the treatment decisions dentists make for MIH-affected teeth.

Abstract Objectives Chitosan is a carbohydrate polymer derived from chitin with a reported antimicrobial effect against bacteria. The present study aimed to investigate the biofilm inhibitory effect of methacrylated chitosan covalently incorporated into the polymethylmethacrylate polymeric network of a denture base resin. Methods Methacrylated chitosan was synthesized by reacting low molecular weight (LMW) chitosan with […]

Interference with bacterial quorum sensing communication provides an anti-virulence strategy to control pathogenic bacteria.

The purpose of this study was to investigate preparations of an anionic porphyrin, meso-tetra-(4-carboxyphenyl)-porphine (TCPP), solubilised in NADES, with regard to their physicochemical and antibacterial properties.

Abstract Medical polymers of biostable nature (e.g. polymethylmetacrylate, PMMA) are widely used in various clinical applications. In this study, novel PMMA-based composite bone cement was prepared. Bioactive glass (BAG) particulate filler (30 wt%) was added to enhance potentially the integration of bone to the cement. The polymer matrix was functionalized with trimethoxysilyl to achieve an interfacial […]

Reduction in the amount of glutathione (GSH) in cells can lead to increased sensitivity to physical and chemical agents. Methacrylate monomers (MM) are precursors of polymethacrylates which are used in dental and medical biomaterials and in a wide variety of other products. MM can increase cell sensitivity to long wavelength ultraviolet and visible radiation. The aim of this study is to elucidate if MM can induce sensitivity also to shorter wavelength radiation.

Powerful blue-light emitting dental curing lights are used in dental offices to photocure resins in the mouth. In addition, many dental personnel use magnification loupes.

Experiments using radial arm mazes show that mice and rats have difficulties finding food when their chewing capability is disturbed after molar extraction. Observations of this kind have indicated an association between mastication and cognition. Experimental evidence show increased blood stream and neuronal activity in young individuals using chewing gum. Some experiments also indicate that […]

It has been suggested that reactive oxygen species are involved in HEMA toxicity. The upregulated levels of antioxidant enzymes and Hsp70 family proteins showed that HEMA exposure lead to cellular stress at concentrations that had no effect on cell viability.

Amalgam was banned as a dental restorative material in Norway in 2008 due to environmental considerations. An electronic questionnaire was sent to all dentists in the member register of the Norwegian Dental Association (NTF) one year later, to evaluate dentists’ satisfaction with alternative restorative materials and to explore dentists’ treatment choices of fractured amalgam restorations.

Abstract Neonatal jaundice, or hyperbilirubinemia, is a relatively common condition, and occurs in 2 out of 3 newborns. The condition is often transient. However, untreated hyperbilirubinemia can cause kernicterus and nervous system damage. Worldwide, over 114 000 infants die and 65 000 infants grow up with permanent brain damage due to this condition [1]. A […]

Some strains of bacteria are known to fluoresce when exposed to UV-light, and are therefore detectable using spectroscopy techniques. If we could differentiate bacteria only based on an image, we open for a range of new methods within the field of microbial diagnostics. This is the underlying idea for our project. As we acquire hyperspectral images of a series of different bacteria, we aim to map their spectral “fingerprint” in a spatial manner. These first investigations make up a feasibility study which is continued this spring to allow for a more complete study.

In Streptococcus mutans, an oral colonizer associated with dental caries, development of competence for natural genetic transformation is triggered by either of two types of peptide pheromones, competence-stimulating

Protein S-glutathionylation (PSSG) is the reversible formation of mixed disulfides between glutathione and protein cysteinyl residues.

Polymer-based restorative materials are widely used in dentistry. Cured materials contain unpolymerized methacrylate monomers which leak into the oral environment.

Snus is a smokeless, ground tobacco product, which is most commonly placed in the mouth between the gum and lip. Like other tobacco products, snus contains the biologically active and addictive substance, nicotine.

The aim was to measure variations in the threshold for operative treatment of occlusal caries in permanent teeth and the use of dental materials, compared with results from a similar study conducted in Norway in 1995.

The European Commission’s independent Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) recently published its risk assessment of exposure to BPA via medical devices that are manufactured with materials that potentially leach BPA leading to oral (via dental material), subcutaneous and intravenous (e.g. during hemodialysis) routes of exposure.