Treatment decisions on Molar-Incisor Hypomineralization (MIH) by Norwegian dentists – a questionnaire study -

The study aimed to explore the variability between the treatment decisions dentists make for MIH-affected teeth.

Anti-biofilm Effect of Methacrylated Chitosan Incorporated Denture Base Resin -

Abstract Objectives Chitosan is a carbohydrate polymer derived from chitin with a reported antimicrobial effect against bacteria. The present study aimed to investigate the biofilm inhibitory effect of methacrylated chitosan covalently incorporated into the polymethylmethacrylate polymeric network of a denture base resin. Methods Methacrylated chitosan was synthesized by reacting low molecular weight (LMW) chitosan with […]

Thiophenone Attenuates Enteropathogenic Escherichia coli O103:H2 Virulence by Interfering with AI-2Signaling -

Interference with bacterial quorum sensing communication provides an anti-virulence strategy to control pathogenic bacteria.

Physicochemical characterisation and antimicrobial phototoxicity of an anionic porphyrin in natural deep eutectic solvents -

The purpose of this study was to investigate preparations of an anionic porphyrin, meso-tetra-(4-carboxyphenyl)-porphine (TCPP), solubilised in NADES, with regard to their physicochemical and antibacterial properties.

Morphological and mechanical characterization of composite bone cement containing polymethylmethacrylate matrix functionalized with trimethoxysilyl and bioactive glass -

Abstract Medical polymers of biostable nature (e.g. polymethylmetacrylate, PMMA) are widely used in various clinical applications. In this study, novel PMMA-based composite bone cement was prepared. Bioactive glass (BAG) particulate filler (30 wt%) was added to enhance potentially the integration of bone to the cement. The polymer matrix was functionalized with trimethoxysilyl to achieve an interfacial […]

Wavelength dependent increase in cell sensitivity after glutathione inhibition by methacrylate monomers. -

Reduction in the amount of glutathione (GSH) in cells can lead to increased sensitivity to physical and chemical agents. Methacrylate monomers (MM) are precursors of polymethacrylates which are used in dental and medical biomaterials and in a wide variety of other products. MM can increase cell sensitivity to long wavelength ultraviolet and visible radiation. The aim of this study is to elucidate if MM can induce sensitivity also to shorter wavelength radiation.

The Dental Curing Light: A Potential Health Risk -

Powerful blue-light emitting dental curing lights are used in dental offices to photocure resins in the mouth. In addition, many dental personnel use magnification loupes.

Oral helse og kognitiv funksjon -

Mus og rotter som får molarer fjernet, finner vanskeligere frem til mat i eksperimentelle labyrinter. Det har ført til spekulasjoner om en sammenheng mellom tyggefunksjon og kognitiv funksjon.

Proteome Changes Indicate Oxidative Stress and Protein Damage after Methacrylate Exposure in Human Monocyte Cell Line -

It has been suggested that reactive oxygen species are involved in HEMA toxicity. The upregulated levels of antioxidant enzymes and Hsp70 family proteins showed that HEMA exposure lead to cellular stress at concentrations that had no effect on cell viability.

The Post-Amalgam Era: Norwegian Dentists’ Experiences with Composite Resins and Repair of Defective Amalgam Restorations -

Amalgam was banned as a dental restorative material in Norway in 2008 due to environmental considerations. An electronic questionnaire was sent to all dentists in the member register of the Norwegian Dental Association (NTF) one year later, to evaluate dentists’ satisfaction with alternative restorative materials and to explore dentists’ treatment choices of fractured amalgam restorations.

Phototherapy with sunlight for treatment of neonatal jaundice in low-income countries -

Abstract Neonatal jaundice, or hyperbilirubinemia, is a relatively common condition, and occurs in 2 out of 3 newborns. The condition is often transient. However, untreated hyperbilirubinemia can cause kernicterus and nervous system damage. Worldwide, over 114 000 infants die and 65 000 infants grow up with permanent brain damage due to this condition [1]. A […]

Hyperspectral fluorescence characterisation of bacteria. -

Some strains of bacteria are known to fluoresce when exposed to UV-light, and are therefore detectable using spectroscopy techniques. If we could differentiate bacteria only based on an image, we open for a range of new methods within the field of microbial diagnostics. This is the underlying idea for our project. As we acquire hyperspectral images of a series of different bacteria, we aim to map their spectral “fingerprint” in a spatial manner. These first investigations make up a feasibility study which is continued this spring to allow for a more complete study.

Comprehensive Transcriptome Profiles of Streptococcus mutans UA159 Map Core Streptococcal Competence Genes -

In Streptococcus mutans, an oral colonizer associated with dental caries, development of competence for natural genetic transformation is triggered by either of two types of peptide pheromones, competence-stimulating

Effect of Components in Resin-Based Dental Restoratives on Protein-S-Glutathionylation -

Protein S-glutathionylation (PSSG) is the reversible formation of mixed disulfides between glutathione and protein cysteinyl residues.

Exposure to Dental Monomer Hydroxyethyl Methacrylate (HEMA) Induces Increased Transcription of Genes Involved in Oxidative Stress Responses -

Polymer-based restorative materials are widely used in dentistry. Cured materials contain unpolymerized methacrylate monomers which leak into the oral environment.

Effekter i munnhulen ved bruk av snus -

Snus is a smokeless, ground tobacco product, which is most commonly placed in the mouth between the gum and lip. Like other tobacco products, snus contains the biologically active and addictive substance, nicotine.

Occlusal Caries Management: Preferences among Dentists in Norway -

The aim was to measure variations in the threshold for operative treatment of occlusal caries in permanent teeth and the use of dental materials, compared with results from a similar study conducted in Norway in 1995.

The safety of the use of bisphenol A in medical devices -

The European Commission’s independent Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) recently published its risk assessment of exposure to BPA via medical devices that are manufactured with materials that potentially leach BPA leading to oral (via dental material), subcutaneous and intravenous (e.g. during hemodialysis) routes of exposure.

Posterior composites and new caries on adjacent surfaces – any association? Longitudinal study with a split-mouth design -

The aim of this longitudinal study was to compare caries incidence in sound approximal surfaces adjacent to newly placed composite restorations with the caries incidence in corresponding surfaces in contralateral teeth without any restorations in contact; and to assess risk factors for dentine caries development on adjacent and control surfaces.

The safety of dental amalgam and alternative dental restoration materials for patients and users -

The European Commission asked its independent Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) to provide a risk assessment on dental amalgam and alternatives such as resin-based composites, glass ionomer cements, ceramics and gold alloys to update the SCENIHR’s 2008 Opinion in light of new developments and data.

Load at fracture of monolithic and bilayered zirconia crowns with and without a cervical zirconia collar -

The effect of anatomic contour design in all or parts of zirconia crowns is uncertain regarding clinical reliability and survival rates.

Toxicity of plast materials -

The term «resin-based dental materials» refers to dental materials containing polymers. Usually, these polymers are formed by in situ polymerization of methacrylate monomers.

Interactions of liposomes with dental restorative materials -

The in vitro adsorption and retention of liposomes onto four common types of dental restorative materials (conventional and silorane-based resin composites as well as conventional and resin-modified glass ionomer cements (GIC)) have been investigated due to their potential use in the oral cavity.

Characterization and antimicrobial phototoxicity of curcumin dissolved in natural deep eutectic solvents -

The purpose of the current study was to evaluate the potential of NADES as a solvent for the hydrophobic photosensitizer curcumin for use in antimicrobial photodynamic therapy (aPDT).

NIOM representation at EDM 2015 -

The 23rd European Dental Materials Conference was held in Nürnberg, Germany, on August 27 and 28, 2015.

Risk factors for caries development on tooth surfaces adjacent to newly placed Class II composites – a pragmatic, practice based study -

To assess risk factors for caries development on approximal surfaces in contact with newly placed Class II composite restorations.

Cyclodextrins influence on lumichrome solubilization and phototoxic efficacy against bacteria. -

Lumichrome (Lc) is a photodegradation product of riboflavin. It is more photostable and a more efficient photogenerator of singlet oxygen than riboflavin. Lc absorbs mainly in the UVA range. Cyclodextrins (CDs) are reported to be very efficient solubility enhancers of Lc in aqueous solutions. A 1:1 inclusion complex has been predicted between Lc and α and βCDs (Terekhova, Kumeev et al. 2011). The aim of the present study was to evaluate the influence of CDs on solubility and on the bacterial phototoxicity of Lc in vitro.

Evaluation of material suitability for nanoparticle-based coatings and further antimicrobial treatment -

Dental materials are easily colonized by bacteria, and microbial attack is the main cause of dental implant failure and periodontitis. The aim of this project was to formulate nanoparticle-based (NPsol) coatings that reduce bacterial adherence on materials used in dentistry. Pre-treatment of the surfaces with such coatings could create a time window that allows for killing of the surrounding bacteria prior to or shortly after adhesion. One option is to apply antimicrobial photodynamic therapy (aPDT).

Silanising agents promote resin-composite repair -

The aim of this study was to investigate the effect of silane in the repair of old and new resin-composite restorations.

In vitro element release and biological aspects of base-metal alloys for metal-ceramic applications -

Abstract Objective The aims of this study were to investigate the release of element from, and the biological response in vitro to, cobalt–chromium alloys and other base–metal alloys used for the fabrication of metal-ceramic restorations. Material and methods: Eighteen different alloys were investigated. Nine cobalt–chromium alloys, three nickel–chromium alloys, two cobalt–chromium–iron alloys, one palladium–silver alloy, […]

Scientific Opinion on the safety of dental amalgam and alternative dental restoration materials for patients and users -

In the light of new developments and studies on dental amalgam a request was submitted by the Commission to update the SCENIHR opinion produced in 2008 on the safety and performance of both dental amalgam and possible alternatives, such as resin-based composites, glass ionomer cements, ceramics and gold alloys.

Evaluation of eye protection in occupational use of non-coherent optical sources -

Blue light and ultraviolet radiation can cause acute eye hazards. Further, increasing evidence suggests that blue light contributes to chronic diseases, such as cataracts and age-related macular degeneration. The use of optical radiation protective devices, such as goggles, is a simple means to avoid eye damage when working with high irradiance sources.

Influence of formulation on photoinactivation of bacteria by lumichrome. -

The aim of this study was to investigate the in vitro aPDT effect of various lumichrome pharmaceutical formulations

The effect of margin curvature on load at fracture of ceramic crowns -

The aim of this study was to use a clinically relevant test method to evaluate the effect of the curvature of the cervical crown margins on load at fracture

Cell toxicity of 2-hydroxyethyl methacrylate (HEMA): the role of oxidative stress -

In this study, the viability of human lung epithelial cells, BEAS-2B, was investigated after exposure to this monomer. Exposure to HEMA reduced the viability of the BEAS-2B cells as a result of increased apoptosis, interruption of the cell cycle, and decreased cell proliferation.

Relative Efficiency Of Ultraviolet Radiation A And B Combined With A Chemical Stressor On Zebrafish Embryos -

Organisms living in aquatic ecosystems may experience high doses of natural UV radiation. UV radiation penetrates the water column down to several meters. The penetration depth differs depending on the contents of particles, dissolved matter or pollutants. The aim of this study was to establish the dose-response relationship of phenotypic changes caused by UV.

Cements for gold inlays -

Gold inlays have for a long time been known as high quality restorations. Since dental amalgam is no longer applicable as filling material in Norway, the need for gold inlays has expanded, especially in patients having high chewing force and tooth abrasions who need replacement of their old amalgam fillings.

Improved antibacterial phototoxicity of a neutral porphyrin in natural deep eutectic solvents -

Neutral porphyrins for antibacterial photodynamic therapy (aPDT) have received little attention due to their tendency to aggregate in aqueous media and reports of low phototoxic effect. These compounds may be less toxic to cells than positively and negatively charged photosensitisers.

Patient satisfaction and complications of over-the-counter bleaching products -

To compare two home-based over-the-counter (OTC) bleaching tray products with similar hydrogen peroxide (HP) concentrations with respect to tooth lightening efficacy and potential to induce negative side effects in tobacco- and non-tobacco users as well as degree of satisfaction with product handling. The HP concentrations were near the regulation limit for bleaching products of 6% set by the European Union in 2011.

Safety of the use of bisphenol A in medical devices -

Bisphenol A (BPA) is a key building block of polycarbonate plastic and a precursor for the manufacturing of monomers of epoxy resins. The BPA exposure of the general population is via food as a result of the use of BPA in food packaging and via skin as a result of contact with thermal paper. The vast majority of the population (91–99%) has detectable levels of BPA-conjugates in their urine. BPA is also present in medical devices including implants, catheters, tubing, and some dental materials.

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