Að mæla ahrif þykktar bindilags og mismunandi yfirborðsmeðferða a viðgerðarstyrk plastblendis.

Despite new strategies in tissue engineering, cartilage repair remains a major challenge. Our aim is to treat
patients with focal lesions of articular cartilage with autologous hyaline cartilage implants using a scaffold-free approach. In this article, we describe experiments to optimize production of scaffold-free cartilage discs.

Advocates of skin protection against blue light express concern about exposure to indoor lighting and electronic screens aswell as natural outdoor exposure. However, the nature of adverse effects in skin is unclear and the doses to induce effectsare unknown. We aimed to reveal whether there is a scientific basis for promoting skin protection against violet-blue […]

Stainless-steel crowns (SSCs) are recommended for restorative treatment of young teeth severely affected by caries, fractures or dental developmental disorders (DDDs). However, despite recommendations and clinical evidence, SSCs are not widely used by general dentists, who favour extraction and more conventional restorations. The present study aimed to investigate the views of and use of SSCs among Norwegian and Finnish dentists.

Mandibular advancement devices (MADs) are used in the treatment of obstructive sleep apnea. A patient (woman in the 60-ies) was treated with a MAD (SomnoDent Fusion Flex; SomnoMed AG). She experienced reactions in form a burning sensation in the mouth, ulcers on the tongue and gingiva, and swelling of the tongue. Allergy test (patch test) with Dental Screening Series showed a strong positive reaction to methyl methacrylate, and clear reactions to ethylene glycol dimethacrylate (EGDMA) and 2-hydroxyethyl methacrylate (HEMA).

The dental community has for a long time been fascinated by the thought of growing a third set of teeth. This has increased research interest in the processes of embryonal development of teeth for experimental copying. However, research of this kind cannot be performed on humans for medical and ethical reasons.

The aim of the study was to investigate Finnish dentists’ knowledge on and means of recording, detecting and
diagnosing erosive tooth wear (ETW). Treatment options and possible differences in treatment decisions
between general and specialized dentists were also evaluated.

The primary aim of root canal treatment of teeth with apical periodontitis is to eliminate the microbial load from the root canal system and promote periapical healing. Meticulous mechanical debridement of the root canal system significantly reduces the bacterial load and is considered important in canal disinfection. However, complete elimination of all microorganisms is challenging, as viable bacteria potentially remain on the dentin walls and inside dentinal tubules, both in planktonic forms and biofilms. About 35% of the root canal area is left untouched when conventional rotary and hand instruments are used. Therefore, disinfection with irrigation solutions during root-canal treatment and thereafter obturation of the root canal are important factors to reduce the amount and growth of residual bacteria.

Protesematerialer inneholder ureagert monomer som kan lekke ut i munnhulen og gi bivirkninger, men i hvor stor grad skjer dette? Tanntekniske laboratorier fremstilte protesematerialer etter sin vanlige metode og NIOM analyserte mengde ureagert monomer, såkalt restmonomer. Kaldakryl hadde større mengde restmonomer enn kokakryl og derfor et større potensiale for å gi bivirkninger. Ett av produktene […]

In this study a method of producing a large number of identical nanostructured surfaces is presented. E. coli wild type and deletion mutants of the type 1 fimbriae monomers FimA or FimH were tested for their ability to adhere to such surfaces with different interpillar distance of 100, 250, and 500 nm, respectively. An increase in interpillar distance (reduced surface coverage) was associated with reduced adhesion of E. coli wild type and the deletion mutants. In addition, the presence of a functional type 1 fimbria decreased adhesion to the nanopatterned surfaces in comparison to deletion mutants, leading us to the conclusion that there is a relationship between presence of a functional fimbriae and adhesion towards tested surfaces. The hypothesis that the presence of fimbriae had an effect on bacterial attachment to nanostructured surfaces was verified. These current results could provide insight into development of new nano-patterned structures with anti-adhesion bacterial properties.

This study showed that the majority of Danish dentists taking part of this survey had adopted a minimally invasive approach for the management of erosive tooth wear in young adults. There was however room for improvements in diagnosis, scoring and case documentation

The use of charcoal for oral hygiene purposes has long traditions in several countries. Products containing charcoal are constantly being introduced to the market, advertising various advantageous properties, such as a whitening effect and detoxification.

Aerosols are generated secondary to different treatment procedures and situations in the dental clinic. Aerosols in the dental clinic may be infectious and transfer disease between clinic staff and patients. The authors present and discuss different measures to reduce infection caused by exposure to microbial aerosols. It is unrealistic to expect that close range aerosols […]

Aerosol-generating procedures associated with oral care may involve risks for disease transmission between patients and dental staff. Article part I describes characteristics of aerosols and possible influence on health. This paper focuses on microbial aerosols and on situations and procedures that produce microbial aerosols in the dental clinic. Several forms of microbial aerosols are created […]

This study investigated the effect of surface nano-patterning on adhesion of an oral early commensal colonizer, Streptococcus mitis and the opportunistic pathogen Staphylococcus aureus and human fibroblasts (HDFa) in a laminar flow cell.

The aim of the study was to investigate the metal ion release, surface roughness and cytoxicity for Co–Cr alloys produced by different manufacturing techniques before and after heat treatment. In addition, to evaluate if the combination of materials affects the ion release.

The aim of the study were to investigate functional and esthetic properties, the composition of the alloy, and the content of hazardous elements of single dental crowns with metal skeleton and fired porcelain.

The aims of this study were to present a novel method to analyse dentin bond strength and to evaluate the bond strength of combining adhesive systems and resin cement from different manufacturers. Based on the results and within the limitations of this laboratory study, it can be concluded that using alternating combinations of resin cement
and adhesives seem possible and that the resin cement were the weakest components in the bonded dentin-adhesive-cement-complex.

The present work suggests that protein profiling in saliva may provide a tool for determining differences in risk for erosive tooth wear. This may be of value when determining lifetime risks of loss of dental structure. To identify the risk at an early stage of the disease gives us the opportunity to implement proper individualized prevention

“Minimally Invasive Dentistry” has over the years been well presented in the Nordic countries as well as in all Europe. Nevertheless, it does no harm to remind ourselves about the principles behind this concept. Based on updated knowledge on caries and tooth wear, in combination with new and improved adhesive restoration techniques, there are good […]

Methacrylate monomers are major components of resin-based biomaterials. The polymerization of these materials is never complete, and methacrylates leaking from cured materials cause exposure of patients. Only some selected methacrylates have thoroughly been tested for possible interaction with living cells. In the current study, we compared the effects of 2-hydroxyethyl-methacrylate (HEMA; a carefully studied methacrylate) […]

Hovedbudskap til helsepersonell

Bruk av svensk snus er forbundet med økt risiko for kreft, høyt blodtrykk, økt dødelighet etter kreft og hjerte- og karsykdommer, økt risiko for psykose, overvekt, metabolsk syndrom – og (ved høyt forbruk) økt risiko for diabetes type 2. Snusbrukere som slutter etter
hjerteinfarkt, halverer risikoen for å dø i tiden etter infarktet. Bruk av snus under svangerskapet er skadelig for barnet. Den høye bruken av snus er derfor bekymringsfull.

Obesity of different degree comprises individuals with a body mass index BMI) of 30 or more and is often combined with cardiovascular and metabolic diseases, whereas overweight below 30 is not. Obesity has a hereditary component combined with environmental factors such as unhealthy food and lack of exercise. In addition, fatty tissue contains inflammatory mediators […]

The aims of this in vitro study were to assess if dynamic loading increases the metal ion release of selected dental alloys and to evaluate the cytotoxicity of the released metal ions

Data on oral health among the elderly in Norway is sparse. The aim of the present study was to describe the distribution of enamel-, dentin-, root- and secondary caries within an elderly population in Northern-Norway. A study population (n=1 173) was divided into four age groups: 65–69, 70–74, 75–79 and 80–94. Seven calibrated examiners registered […]

The study showed that the average prevalence of MIH among children of 8 years in Helsinki was comparable to that reported elsewhere. The number of MIH-affected teeth at early mixed dentition predicts the affection of other permanent teeth over time, mainly that of permanent canines. An irrelevant number of children had MIH-affected second primary molars. Further screening of children with MIH-affected teeth is recommended to improve individually tailored early preventive and restorative dental care. In this way, an early intervention will facilitate management of further clinical dental problems of MIH-affected teeth and improve oral health-related quality of life of children with this condition.

Salivary flow rate exerts an essential impact on the development and progression of dental erosion. In this work, the experimental dental erosion in non-obese diabetic (NOD) mice with reduced salivary flow rate was induced, and the erosive effect of acidic drinks on their dentition was studied.

This survey shows that Finnish dentists are rather homogeneous in their treatment decisions when managing primary tooth caries or a severely affected MIH tooth, although some practices vary between general and specialised dentists. Moreover, the disparity in treatment practices between different areas of Finland is evident. The proportion of SSC as a material choice was low. Patient co-operation plays a big role in treatment decisions and may explain why GICs were the most popular choice for restoring extensive primary tooth caries. The emphasis should be on behavioural management as well as on the evidence-based treatment recommendations.

There is no generally accepted protocol for resin composites that simulates and accelerates ageing of the materials under oral conditions. Even though thermal cycling is one of the procedures used to seriously try to simulate physiological aging of restorative materials, review of the literature on thermal cycling procedures shows that there is little or no consistency in protocols and variables. This makes it difficult to compare results from the various investigations. Selection of variables like size of specimens, storage time, and dwell times in water baths, transfer time and number of cycles, appear to be selected by investigators mostly based on convenience rather than referenced observations or scientifically founded facts

Dental erosive wear is a multifactorial condition of high prevalence. Nowadays, there is an emphasis on discovering individual genetic predisposition for the development of this condition. Aquaporins (AQPs) are water channel proteins expressed in salivary glands, as well as during tooth development. They are involved in salivary secretion and composition and linked to physiological protection of the oral cavity.
The aim of this study was to explore the relationship between different dental erosive wear phenotypes, AQP genes, and selected environmental factors.

Thin films of metal–organic frameworks (MOFs) are promising for a wide range of applications including membranes for separations and sensor materials in microelectronics. Growth of such thin films using atomic/molecular layer deposition (ALD/MLD) has recently been demonstrated; however, the range of examples is still narrow. Here, we expand the repertory of gas-phase MOF thin film […]

The guidelines provide a framework to perform a BRA to justify the presence of CMR or ED phthalates in medical devices.
They also describe the evaluation of possible alternatives for these phthalates used in medical devices.
Manufacturers are encouraged to generate data that are needed for the BRA on potential alternatives to be used in medical devices.

Bruk av snus under svangerskapet er skadelig for mor og barn. Dette budskapet må leger og annet helsepersonell videreformidle til sine pasienter, sånn at flest mulig kvinner i fertil alder legger vekk snusen før de blir gravide. Snus og andre nikotinerstatningsmidler er ikke risikofrie alternativer til røyking.

Age related changes in chewing muscles and tongue take place parallel with neurological changes in the stomatognatic system. Deterioration of this kind may lead to swallowing difficulties accompanied by coughing, discomfort, and aspiration of solid or fluid material into the airways. This condition is denoted dysphagia and is often associated with cardiovascular and neurological diseases […]

The present study showed that a ZOE-based material has an antibacterial effect and that incorporating CH or COS may increase the antibacterial effect depending on the bacterial species. The total release of eugenol from the materials was stable for up to 18 weeks immersion in water. Eugenol therefore contributed to the antibacterial effect on all the material surfaces investigated. S. mutans exhibited the highest susceptibility to eugenol. The compressive strength of the modified materials was reduced but still met the requirements in ISO 3017.

The Scientific Committee on Health, Environmental and Emerging Risks of the European Commission adopted this document at plenary meeting on 18 June 2019.
NIOM Scientist and Head of Laboratory, Hilde M. Kopperud served as external expert.

The aim of this study was to evaluate the dentine bond strength of a novel fast‐setting calcium silicate cement (Protooth) versus a calcium hydroxide‐based cement (Dycal), a calcium silicate cement (ProRoot MTA), and a glass ionomer cement (Ketac‐Molar). Mid‐root dentine slices of 1 mm thickness were obtained from human maxillary incisors. After enlarging the lumen […]

Dental erosion has a multifactorial etiology with contributions from chemical, biological and behavioral factors. In terms of chemical factors, type of foods and drinks is important. The chemical factors that determine whether foods and drinks are erosive are low pH, type of acid, meaning a low acid dissociation constant (pKa), high buffer capacity and low […]

Abstract from Håkon Valens lecture at symposium PDT-4. Human antimicrobial PDT. ESP-IUPB World Congress, Light & Life, Barcelona, Spain. August 25-30. 2019. Bacteria in the oral cavity lives primarily in polymicrobial biofilms. Oral mature biofilms may contain several hundred different bacterial species, and over 600 different species have been shown to colonize the oral cavity. […]

Abstract from Håkon Valens lecture at symposium MED-10 Dentistry. (Organized by Ellen Bruzell). ESP-IUPB World Congress, Light & Life, Barcelona, Spain. August 25-30. 2019. Oral biofilm formation around teeth and dental implants may cause inflammation of the surrounding tissue, which may lead to breakdown of the attachment of the tooth or implant. Ultimately, if left […]