The sensitization potential of two orthodontic bonding materials, one conventional premix product and one nonmix product, was evaluated by a modified guinea pig maximization test. The nonmix product, consisting of a liquid to be applied to the tooth surface and a paste which was placed on the bracket base, caused reaction in 50% of the tested animals. This material should be considered to be a possible cause of allergy in patients or professionals handling it.
Allergenic potential of two orthodontic bonding materials
Søhoel HC, Gjerdet N, Hensten-Pettersen A, Ruyter E
Scandinavian Journal of Dental Research 1994; 102: 126-129.